Symbol: Name: ID: |
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 GFS:5962 |
Gene name: | ARNT2 |
Chromosome: | 15q25.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KIAA0307, bHLHe1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:107188 | Rat Genome Database ID: | RGD:2154 |
HGNC ID: | HGNC:16876 | RefSeq IDs: | NM_014862 |
Entrez Gene ID: | 9915 | Ensembl Gene ID: | ENSG00000172379 |
VEGA IDs: | OTTHUMG00000138508 | UniProt ID: | Q9HBZ2 |
UCSC ID: | uc002bfr.2 | OMIM ID: | 606036 |
Pubmed: | PMID11247670 | ||
CCDS IDs: | CCDSCCDS32307.1 |
Aryl hydrocarbon receptor nuclear translocator 2 is a protein that in humans is encoded by the ARNT2 gene.
This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Specifically recognizes the xenobiotic response element (XRE).
Products for ARNT2 gene
Catalog | Product Name | Application | Company |
GFS:E05962 | aryl-hydrocarbon receptor nuclear translocator 2; ELISA kit | ELISA | n/a |
GFS:A05962 | aryl-hydrocarbon receptor nuclear translocator 2; Anti | ANTIBODIES | n/a |
GFS:P05962 | aryl-hydrocarbon receptor nuclear translocator 2; Protien | Protien | n/a |