Symbol: Name: ID: |
ANAPC7 anaphase promoting complex subunit 7 GFS:6458 |
Gene name: | ANAPC7 |
Chromosome: | 12q13.12 |
Previous Symbols: | |
Previous Names: | |
Aliases: | APC7 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1929711 | Rat Genome Database ID: | RGD:1311927 |
HGNC ID: | HGNC:17380 | RefSeq IDs: | NM_001137664 |
Entrez Gene ID: | 51434 | Ensembl Gene ID: | ENSG00000196510 |
VEGA IDs: | OTTHUMG00000157009 | UniProt ID: | Q9UJX3 |
UCSC ID: | uc001tqo.2 | OMIM ID: | 606949 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS9145.2 CCDS CCDS44971.1 |
Anaphase-promoting complex subunit 7 is an enzyme that in humans is encoded by the ANAPC7 gene.
This gene encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008].
Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Products for ANAPC7 gene
Catalog | Product Name | Application | Company |
GFS:E06458 | anaphase promoting complex subunit 7; ELISA kit | ELISA | n/a |
GFS:A06458 | anaphase promoting complex subunit 7; Anti | ANTIBODIES | n/a |
GFS:P06458 | anaphase promoting complex subunit 7; Protien | Protien | n/a |