Symbol: Name: ID: |
ULBP3 UL16 binding protein 3 GFS:4182 |
Gene name: | ULBP3 |
Chromosome: | 6q25 |
Previous Symbols: | |
Previous Names: | |
Aliases: | RAET1N |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:14895 | RefSeq IDs: | NM_024518 |
Entrez Gene ID: | 79465 | Ensembl Gene ID: | ENSG00000131019 |
VEGA IDs: | OTTHUMG00000015811 | UniProt ID: | Q9BZM4 |
UCSC ID: | uc003qns.3 | OMIM ID: | 605699 |
Pubmed: | PMID11239445 PMID 11827464 | ||
CCDS IDs: | CCDSCCDS5225.1 |
NKG2D ligand 3 is a protein that in humans is encoded by the ULBP3 gene.
Function: Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP2. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. Has lower affinity for NKG2D compared to ULBP1 and ULBP2 and induces weaker signaling responses than does ULBP2 or ULBP1.
Products for ULBP3 gene
Catalog | Product Name | Application | Company |
GFS:E04182 | UL16 binding protein 3; ELISA kit | ELISA | n/a |
GFS:A04182 | UL16 binding protein 3; Anti | ANTIBODIES | n/a |
GFS:P04182 | UL16 binding protein 3; Protien | Protien | n/a |