| Symbol: Name: ID: |
TSC22D1 TSC22 domain family, member 1 GFS:5912 |
| Gene name: | TSC22D1 |
| Chromosome: | 13q14 |
| Previous Symbols: | TGFB1I4 |
| Previous Names: | transforming growth factor beta 1 induced transcript 4 |
| Aliases: | TSC22, MGC17597 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:109127 | Rat Genome Database ID: | |
| HGNC ID: | HGNC:16826 | RefSeq IDs: | NM_006022 |
| Entrez Gene ID: | 8848 | Ensembl Gene ID: | ENSG00000102804 |
| VEGA IDs: | OTTHUMG00000016838 | UniProt ID: | Q15714 |
| UCSC ID: | uc001uzn.3 | OMIM ID: | 607715 |
| Pubmed: | PMID8651929 PMID 9022669 | ||
| CCDS IDs: | CCDSCCDS9392.1 CCDS CCDS31966.1 | ||
TSC22 domain family protein 1 is a protein that in humans is encoded by the TSC22D1 gene.
TSC22 encodes a transcription factor and belongs to the large family of early response genes.
TSC22D1 forms homodimers via its conserved leucine zipper domain and heterodimerizes with TSC22D4. TSC22D1 has transcriptional repressor activity
This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011].
Function: Transcriptional repressor. Acts on the C-type natriuretic peptide (CNP) promoter.
Products for TSC22D1 gene
| Catalog | Product Name | Application | Company |
| GFS:E05912 | TSC22 domain family, member 1; ELISA kit | ELISA | n/a |
| GFS:A05912 | TSC22 domain family, member 1; Anti | ANTIBODIES | n/a |
| GFS:P05912 | TSC22 domain family, member 1; Protien | Protien | n/a |
