Symbol: Name: ID: |
TIMP4 TIMP metallopeptidase inhibitor 4 GFS:1638 |
Gene name: | TIMP4 |
Chromosome: | 3p25 |
Previous Symbols: | |
Previous Names: | tissue inhibitor of metalloproteinase 4 |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:109125 | Rat Genome Database ID: | |
HGNC ID: | HGNC:11823 | RefSeq IDs: | NM_003256 |
Entrez Gene ID: | 7079 | Ensembl Gene ID: | ENSG00000157150 |
VEGA IDs: | OTTHUMG00000129763 | UniProt ID: | Q99727 |
UCSC ID: | uc003bwo.2 | OMIM ID: | 601915 |
Pubmed: | PMID8939999 PMID 9693046 | ||
CCDS IDs: | CCDSCCDS2608.1 |
Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene. This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.
Products for TIMP4 gene
Catalog | Product Name | Application | Company |
GFS:E01638 | TIMP metallopeptidase inhibitor 4; ELISA kit | ELISA | n/a |
GFS:A01638 | TIMP metallopeptidase inhibitor 4; Anti | ANTIBODIES | n/a |
GFS:P01638 | TIMP metallopeptidase inhibitor 4; Protien | Protien | n/a |