Symbol: Name: ID: |
SEC61B Sec61 beta subunit GFS:6083 |
Gene name: | SEC61B |
Chromosome: | 9q22.32-q31.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1913462 | Rat Genome Database ID: | RGD:1304997 |
HGNC ID: | HGNC:16993 | RefSeq IDs: | NM_006808 |
Entrez Gene ID: | 10952 | Ensembl Gene ID: | ENSG00000106803 |
VEGA IDs: | OTTHUMG00000020354 | UniProt ID: | P60468 |
UCSC ID: | uc004azh.2 | OMIM ID: | 609214 |
Pubmed: | PMID8107851 PMID 10212142 | ||
CCDS IDs: | CCDSCCDS6741.1 |
Protein transport protein Sec61 subunit beta is a protein that in humans is encoded by the SEC61B gene.
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Necessary for protein translocation in the endoplasmic reticulum.
Products for SEC61B gene
Catalog | Product Name | Application | Company |
GFS:E06083 | Sec61 beta subunit; ELISA kit | ELISA | n/a |
GFS:A06083 | Sec61 beta subunit; Anti | ANTIBODIES | n/a |
GFS:P06083 | Sec61 beta subunit; Protien | Protien | n/a |