Symbol: Name: ID: |
SIX5 SIX homeobox 5 GFS:799 |
Gene name: | SIX5 |
Chromosome: | 19q13.32 |
Previous Symbols: | DMAHP |
Previous Names: | sine oculis homeobox (Drosophila) homolog 5, "sine oculis homeobox homolog 5 (Drosophila)" |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:106220 | Rat Genome Database ID: | RGD:1305040 |
HGNC ID: | HGNC:10891 | RefSeq IDs: | NM_175875 |
Entrez Gene ID: | 147912 | Ensembl Gene ID: | ENSG00000177045 |
VEGA IDs: | UniProt ID: | Q8N196 | |
UCSC ID: | uc002pdb.2 | OMIM ID: | 600963 |
Pubmed: | PMID8595416 | ||
CCDS IDs: | CCDSCCDS12673.1 |
Homeodomain transcription factor is a protein that in humans is encoded by the SIX5 gene. The protein encoded by this gene is a homeodomain-containing transcription factor that appears to function in the regulation of organogenesis. This gene is located downstream of the dystrophia myotonica-protein kinase gene. Mutations in this gene are a cause of branchiootorenal syndrome type 2. [provided by RefSeq]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5'-GGTGTCAG-3' motif present in the ARE regulatory element of ATP1A1. Binds a 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter (By similarity). Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3 (By similarity).
Products for SIX5 gene
Catalog | Product Name | Application | Company |
GFS:E00799 | SIX homeobox 5; ELISA kit | ELISA | n/a |
GFS:A00799 | SIX homeobox 5; Anti | ANTIBODIES | n/a |
GFS:P00799 | SIX homeobox 5; Protien | Protien | n/a |