Symbol: Name: ID: |
TSIX XIST antisense RNA (non-protein coding) GFS:2181 |
Gene name: | TSIX |
Chromosome: | Xq13.2 |
Previous Symbols: | |
Previous Names: | X (inactive)-specific transcript, antisense |
Aliases: | NCRNA00013, XIST-AS |
Name Aliases: | non-protein coding RNA 13 |
Locus Type: | RNA, antisense |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:12377 | RefSeq IDs: | NR_003255 |
Entrez Gene ID: | 9383 | Ensembl Gene ID: | |
VEGA IDs: | UniProt ID: | ||
UCSC ID: | uc004ebn.2 | OMIM ID: | 300181 |
Pubmed: | PMID10192391 | ||
CCDS IDs: |
In mammals, dosage compensation of genes on the X chromosome occurs by X inactivation, which is regulated in cis by the X-inactivation center (XIC) and expression of the XIST non-coding RNA. This gene expresses a non-coding antisense transcript across the 3' end of the XIST locus, and is coexpressed with XIST only from the inactive X chromosome. The mouse ortholog of this locus is required for imprinted X inactivation in extraembryonic tissues and silences Xist through modification of the chromatin structure in the Xist promoter region. In contrast, imprinted X inactivation does not occur in human extraembryonic tissues and transcripts from this locus do not repress XIST expression or affect random X chromosome inactivation in embryonic cells. This transcript is thought to be unspliced and extend over more than 30 kb, but its exact nature has not been determined. [provided by RefSeq]. Sequence Note: The RefSeq transcript was derived from the reference genome assembly. The genomic coordinates were determined from alignments.
Products for TSIX gene
Catalog | Product Name | Application | Company |
GFS:E02181 | XIST antisense RNA (non-protein coding); ELISA kit | ELISA | n/a |
GFS:A02181 | XIST antisense RNA (non-protein coding); Anti | ANTIBODIES | n/a |
GFS:P02181 | XIST antisense RNA (non-protein coding); Protien | Protien | n/a |