Symbol: Name: ID: |
SH3BGRL3 SH3 domain binding glutamic acid-rich protein like 3 GFS:4763 |
Gene name: | SH3BGRL3 |
Chromosome: | 1p36.11 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1920973 | Rat Genome Database ID: | RGD:1308118 |
HGNC ID: | HGNC:15568 | RefSeq IDs: | NM_031286 |
Entrez Gene ID: | 83442 | Ensembl Gene ID: | ENSG00000142669 |
VEGA IDs: | OTTHUMG00000003381 | UniProt ID: | Q9H299 |
UCSC ID: | uc001blu.2 | OMIM ID: | |
Pubmed: | |||
CCDS IDs: | CCDSCCDS278.1 |
SH3 domain-binding glutamic acid-rich-like protein 3 is a protein that in humans is encoded by the SH3BGRL3 gene.
The 10.5kDa protein SH3 binding glutamic acid-rich protein-like 3 has an isoelectric point of 5.0. SH3 binding glutamic acid-rich (SH3BGR) gene is located to human chromosome 21. Two homologous genes, SH3BGRL and SH3BGRL3 are located to chromosome Xq13.3 and 1p34.3-35, respectively and code for small proteins similar to the N-terminal region of the SH3BGR protein. SH3BGRL3 protein shows a significant similarity to glutaredoxin 1 of E. coli, and all the three proteins are predicted to belong to thioredoxin-like protein family. Glutaredoxins (GRXs) are ubiquitous oxidoreductases, which catalyze the reduction of many intra-cellular protein disulfides and play an important role in many redox pathways. However, the SH3BGRL3 protein lacks the enzymatic function of glutaredoxins and may have a role as a regulator of redox activity.
Function: Could act as a modulator of glutaredoxin biological activity.
Products for SH3BGRL3 gene
Catalog | Product Name | Application | Company |
GFS:E04763 | SH3 domain binding glutamic acid-rich protein like 3; ELISA kit | ELISA | n/a |
GFS:A04763 | SH3 domain binding glutamic acid-rich protein like 3; Anti | ANTIBODIES | n/a |
GFS:P04763 | SH3 domain binding glutamic acid-rich protein like 3; Protien | Protien | n/a |