Symbol: Name: ID: |
SH2D2A SH2 domain containing 2A GFS:736 |
Gene name: | SH2D2A |
Chromosome: | 1q21 |
Previous Symbols: | |
Previous Names: | SH2 domain protein 2A |
Aliases: | TSAd, F2771 |
Name Aliases: | T lymphocyte specific adaptor protein, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1351596 | Rat Genome Database ID: | RGD:1303076 |
HGNC ID: | HGNC:10821 | RefSeq IDs: | NM_001161441 |
Entrez Gene ID: | 9047 | Ensembl Gene ID: | ENSG00000027869 |
VEGA IDs: | OTTHUMG00000041305 | UniProt ID: | Q9NP31 |
UCSC ID: | uc001fqd.2 | OMIM ID: | 604514 |
Pubmed: | PMID9468509 | ||
CCDS IDs: | CCDSCCDS1159.1 |
SH2 domain-containing protein 2A is a protein that in humans is encoded by the SH2D2A gene. This gene encodes an adaptor protein thought to function in T-cell signal transduction. A related protein in mouse is responsible for the activation of lymphocyte-specific protein-tyrosine kinase and functions in downstream signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Could be a T-cell-specific adapter protein involved in the control of T-cell activation. May play a role in the CD4-p56-LCK-dependent signal transduction pathway. Could also play an important role in normal and pathological angiogenesis. Could be an adapter protein that facilitates and regulates interaction of KDR with effector proteins important to endothelial cell survival and proliferation.
Products for SH2D2A gene
Catalog | Product Name | Application | Company |
GFS:E00736 | SH2 domain containing 2A; ELISA kit | ELISA | n/a |
GFS:A00736 | SH2 domain containing 2A; Anti | ANTIBODIES | n/a |
GFS:P00736 | SH2 domain containing 2A; Protien | Protien | n/a |