Symbol: Name: ID: |
RBM38 RNA binding motif protein 38 GFS:4960 |
Gene name: | RBM38 |
Chromosome: | 20q13.31 |
Previous Symbols: | RNPC1 |
Previous Names: | RNA-binding region (RNP1, RRM) containing 1 |
Aliases: | HSRNASEB, SEB4D, seb4B, dJ800J21.2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1889294 | Rat Genome Database ID: | RGD:1308503 |
HGNC ID: | HGNC:15818 | RefSeq IDs: | NM_017495 |
Entrez Gene ID: | 55544 | Ensembl Gene ID: | ENSG00000132819 |
VEGA IDs: | OTTHUMG00000032820 | UniProt ID: | Q9H0Z9 |
UCSC ID: | uc010zzj.1 | OMIM ID: | 612428 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS46617.1 CCDS CCDS46618.1 |
Function: RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.
Products for RBM38 gene
Catalog | Product Name | Application | Company |
GFS:E04960 | RNA binding motif protein 38; ELISA kit | ELISA | n/a |
GFS:A04960 | RNA binding motif protein 38; Anti | ANTIBODIES | n/a |
GFS:P04960 | RNA binding motif protein 38; Protien | Protien | n/a |