Symbol: Name: ID: |
RBM17 RNA binding motif protein 17 GFS:6033 |
Gene name: | RBM17 |
Chromosome: | 10p15.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | SPF45, MGC14439 |
Name Aliases: | splicing factor 45kDa |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1924188 | Rat Genome Database ID: | RGD:1311208 |
HGNC ID: | HGNC:16944 | RefSeq IDs: | NM_001145547 |
Entrez Gene ID: | 84991 | Ensembl Gene ID: | ENSG00000134453 |
VEGA IDs: | OTTHUMG00000017618 | UniProt ID: | Q96I25 |
UCSC ID: | uc001ijb.2 | OMIM ID: | 606935 |
Pubmed: | PMID9731529 | ||
CCDS IDs: | CCDSCCDS7077.1 |
Splicing factor 45 is a protein that in humans is encoded by the RBM17 gene.
This gene encodes an RNA binding protein. The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 9 and 15. [provided by RefSeq, Mar 2009].
Function: Splice factor that binds to the single stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. Promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene. The resulting frameshift leads to sickle cell anemia.
Products for RBM17 gene
Catalog | Product Name | Application | Company |
GFS:E06033 | RNA binding motif protein 17; ELISA kit | ELISA | n/a |
GFS:A06033 | RNA binding motif protein 17; Anti | ANTIBODIES | n/a |
GFS:P06033 | RNA binding motif protein 17; Protien | Protien | n/a |