Symbol: Name: ID: |
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) GFS:3859 |
Gene name: | RASGRP3 |
Chromosome: | 2p25.1-p24.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KIAA0846, GRP3 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:3028579 | Rat Genome Database ID: | RGD:1304612 |
HGNC ID: | HGNC:14545 | RefSeq IDs: | NM_001139488 |
Entrez Gene ID: | 25780 | Ensembl Gene ID: | ENSG00000152689 |
VEGA IDs: | OTTHUMG00000152124 | UniProt ID: | Q8IV61 |
UCSC ID: | uc002roy.2 | OMIM ID: | 609531 |
Pubmed: | PMID10048485 PMID 10934204 | ||
CCDS IDs: | CCDSCCDS46256.1 |
Ras guanyl-releasing protein 3 is a protein that in humans is encoded by the RASGRP3 gene.
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008].
Function: Guanine nucleotide exchange factor (GEF) for Ras and Rap1.
Products for RASGRP3 gene
Catalog | Product Name | Application | Company |
GFS:E03859 | RAS guanyl releasing protein 3 (calcium and DAG-regulated); ELISA kit | ELISA | n/a |
GFS:A03859 | RAS guanyl releasing protein 3 (calcium and DAG-regulated); Anti | ANTIBODIES | n/a |
GFS:P03859 | RAS guanyl releasing protein 3 (calcium and DAG-regulated); Protien | Protien | n/a |