Symbol: Name: ID: |
PDZD2 PDZ domain containing 2 GFS:7332 |
Gene name: | PDZD2 |
Chromosome: | 5p14.1 |
Previous Symbols: | PDZK3 |
Previous Names: | PDZ domain containing 3 |
Aliases: | KIAA0300 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1922394 | Rat Genome Database ID: | RGD:619958 |
HGNC ID: | HGNC:18486 | RefSeq IDs: | NM_178140 |
Entrez Gene ID: | 23037 | Ensembl Gene ID: | ENSG00000133401 |
VEGA IDs: | UniProt ID: | O15018 | |
UCSC ID: | uc003jhm.2 | OMIM ID: | 610697 |
Pubmed: | PMID9205841 | ||
CCDS IDs: | CCDSCCDS34137.1 |
PDZ domain-containing protein 2 is a protein that in humans is encoded by the PDZD2 gene.
Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for PDZD2 gene
Catalog | Product Name | Application | Company |
GFS:E07332 | PDZ domain containing 2; ELISA kit | ELISA | n/a |
GFS:A07332 | PDZ domain containing 2; Anti | ANTIBODIES | n/a |
GFS:P07332 | PDZ domain containing 2; Protien | Protien | n/a |