Symbol: Name: ID: |
NKIRAS2 NFKB inhibitor interacting Ras-like 2 GFS:6798 |
Gene name: | NKIRAS2 |
Chromosome: | 17q21.31 |
Previous Symbols: | |
Previous Names: | NFKB inhibitor interacting Ras-like protein 2 |
Aliases: | KBRAS2, DKFZP434N1526, kappaB-Ras2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1919216 | Rat Genome Database ID: | RGD:1307363 |
HGNC ID: | HGNC:17898 | RefSeq IDs: | NM_001001349 |
Entrez Gene ID: | 28511 | Ensembl Gene ID: | ENSG00000168256 |
VEGA IDs: | OTTHUMG00000133503 | UniProt ID: | Q9NYR9 |
UCSC ID: | uc002hys.2 | OMIM ID: | 604497 |
Pubmed: | PMID10657303 | ||
CCDS IDs: | CCDSCCDS11415.1 CCDS CCDS45679.1 CCDS CCDS45680.1 |
Function: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (By similarity).
Products for NKIRAS2 gene
Catalog | Product Name | Application | Company |
GFS:E06798 | NFKB inhibitor interacting Ras-like 2; ELISA kit | ELISA | n/a |
GFS:A06798 | NFKB inhibitor interacting Ras-like 2; Anti | ANTIBODIES | n/a |
GFS:P06798 | NFKB inhibitor interacting Ras-like 2; Protien | Protien | n/a |