| Symbol: Name: ID: |
NKIRAS2 NFKB inhibitor interacting Ras-like 2 GFS:6798 |
| Gene name: | NKIRAS2 |
| Chromosome: | 17q21.31 |
| Previous Symbols: | |
| Previous Names: | NFKB inhibitor interacting Ras-like protein 2 |
| Aliases: | KBRAS2, DKFZP434N1526, kappaB-Ras2 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1919216 | Rat Genome Database ID: | RGD:1307363 |
| HGNC ID: | HGNC:17898 | RefSeq IDs: | NM_001001349 |
| Entrez Gene ID: | 28511 | Ensembl Gene ID: | ENSG00000168256 |
| VEGA IDs: | OTTHUMG00000133503 | UniProt ID: | Q9NYR9 |
| UCSC ID: | uc002hys.2 | OMIM ID: | 604497 |
| Pubmed: | PMID10657303 | ||
| CCDS IDs: | CCDSCCDS11415.1 CCDS CCDS45679.1 CCDS CCDS45680.1 | ||
Function: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (By similarity).
Products for NKIRAS2 gene
| Catalog | Product Name | Application | Company |
| GFS:E06798 | NFKB inhibitor interacting Ras-like 2; ELISA kit | ELISA | n/a |
| GFS:A06798 | NFKB inhibitor interacting Ras-like 2; Anti | ANTIBODIES | n/a |
| GFS:P06798 | NFKB inhibitor interacting Ras-like 2; Protien | Protien | n/a |