| Symbol: Name: ID: |
NKIRAS1 NFKB inhibitor interacting Ras-like 1 GFS:6799 |
| Gene name: | NKIRAS1 |
| Chromosome: | 3p24.1 |
| Previous Symbols: | |
| Previous Names: | NFKB inhibitor interacting Ras-like protein 1 |
| Aliases: | KBRAS1, kappaB-Ras1 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1916971 | Rat Genome Database ID: | RGD:1308560 |
| HGNC ID: | HGNC:17899 | RefSeq IDs: | NM_020345 |
| Entrez Gene ID: | 28512 | Ensembl Gene ID: | ENSG00000197885 |
| VEGA IDs: | OTTHUMG00000155605 | UniProt ID: | Q9NYS0 |
| UCSC ID: | uc003ccj.2 | OMIM ID: | 604496 |
| Pubmed: | PMID10657303 | ||
| CCDS IDs: | CCDSCCDS33717.1 | ||
Function: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
Products for NKIRAS1 gene
| Catalog | Product Name | Application | Company |
| GFS:E06799 | NFKB inhibitor interacting Ras-like 1; ELISA kit | ELISA | n/a |
| GFS:A06799 | NFKB inhibitor interacting Ras-like 1; Anti | ANTIBODIES | n/a |
| GFS:P06799 | NFKB inhibitor interacting Ras-like 1; Protien | Protien | n/a |
