Symbol: Name: ID: |
MLX MAX-like protein X GFS:1490 |
Gene name: | MLX |
Chromosome: | 17q21.1 |
Previous Symbols: | TCFL4 |
Previous Names: | transcription factor-like 4 |
Aliases: | MAD7, MXD7, bHLHd13 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:108398 | Rat Genome Database ID: | RGD:1308590 |
HGNC ID: | HGNC:11645 | RefSeq IDs: | NM_170607 |
Entrez Gene ID: | 6945 | Ensembl Gene ID: | ENSG00000108788 |
VEGA IDs: | UniProt ID: | Q9UH92 | |
UCSC ID: | uc002iag.2 | OMIM ID: | 602976 |
Pubmed: | PMID8973301 | ||
CCDS IDs: | CCDSCCDS11430.1 CCDS CCDS42341.1 CCDS CCDS45687.1 |
Max-like protein X is a protein that in humans is encoded by the MLX gene. The product of this gene belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. This gene product may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq].
Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.
Products for MLX gene
Catalog | Product Name | Application | Company |
GFS:E01490 | MAX-like protein X; ELISA kit | ELISA | n/a |
GFS:A01490 | MAX-like protein X; Anti | ANTIBODIES | n/a |
GFS:P01490 | MAX-like protein X; Protien | Protien | n/a |