| Symbol: Name: ID: |
MLXIPL MLX interacting protein-like GFS:2512 |
| Gene name: | MLXIPL |
| Chromosome: | 7q11.23 |
| Previous Symbols: | WBSCR14 |
| Previous Names: | Williams Beuren syndrome chromosome region 14 |
| Aliases: | WS-bHLH, MIO, CHREBP, MONDOB, bHLHd14 |
| Name Aliases: | carbohydrate response element binding protein |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1927999 | Rat Genome Database ID: | |
| HGNC ID: | HGNC:12744 | RefSeq IDs: | NM_032951 |
| Entrez Gene ID: | 51085 | Ensembl Gene ID: | ENSG00000009950 |
| VEGA IDs: | OTTHUMG00000129995 | UniProt ID: | Q9NP71 |
| UCSC ID: | uc003tyn.1 | OMIM ID: | 605678 |
| Pubmed: | PMID9860302 | ||
| CCDS IDs: | CCDSCCDS5553.1 CCDS CCDS5554.1 CCDS CCDS47605.1 CCDS CCDS47606.1 | ||
Williams-Beuren syndrome chromosomal region 14 protein is a protein that in humans is encoded by the MLXIPL gene. The protein is also known as Carbohydrate Response Element Binding Protein for its interaction with carbohydrate response element sequences of DNA.
This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. [provided by RefSeq].
Function: Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3' (By similarity).
Products for MLXIPL gene
| Catalog | Product Name | Application | Company |
| GFS:E02512 | MLX interacting protein-like; ELISA kit | ELISA | n/a |
| GFS:A02512 | MLX interacting protein-like; Anti | ANTIBODIES | n/a |
| GFS:P02512 | MLX interacting protein-like; Protien | Protien | n/a |
