Symbol: Name: ID: |
MRGPRX2 MAS-related GPR, member X2 GFS:6878 |
Gene name: | MRGPRX2 |
Chromosome: | 11p15.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | MRGX2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:3588270 | Rat Genome Database ID: | RGD:738048 |
HGNC ID: | HGNC:17983 | RefSeq IDs: | NM_054030 |
Entrez Gene ID: | 117194 | Ensembl Gene ID: | ENSG00000183695 |
VEGA IDs: | UniProt ID: | Q96LB1 | |
UCSC ID: | uc001mph.2 | OMIM ID: | 607228 |
Pubmed: | PMID11551509 | ||
CCDS IDs: | CCDSCCDS7847.1 |
Mas-related G-protein coupled receptor member X2 is a protein that in humans is encoded by the MRGPRX2 gene.
Function: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled.
Products for MRGPRX2 gene
Catalog | Product Name | Application | Company |
GFS:E06878 | MAS-related GPR, member X2; ELISA kit | ELISA | n/a |
GFS:A06878 | MAS-related GPR, member X2; Anti | ANTIBODIES | n/a |
GFS:P06878 | MAS-related GPR, member X2; Protien | Protien | n/a |