Symbol: Name: ID: |
MRGPRX1 MAS-related GPR, member X1 GFS:6860 |
Gene name: | MRGPRX1 |
Chromosome: | 11p15.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | MRGX1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2441674 | Rat Genome Database ID: | |
HGNC ID: | HGNC:17962 | RefSeq IDs: | NM_147199 |
Entrez Gene ID: | 259249 | Ensembl Gene ID: | ENSG00000170255 |
VEGA IDs: | UniProt ID: | Q96LB2 | |
UCSC ID: | uc001mpg.2 | OMIM ID: | 607227 |
Pubmed: | PMID11551509 | ||
CCDS IDs: | CCDSCCDS7846.1 |
Mas-related G-protein coupled receptor member X1 is a protein that in humans is encoded by the MRGPRX1 gene.
Function: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in an histamine-independent manner.
Products for MRGPRX1 gene
Catalog | Product Name | Application | Company |
GFS:E06860 | MAS-related GPR, member X1; ELISA kit | ELISA | n/a |
GFS:A06860 | MAS-related GPR, member X1; Anti | ANTIBODIES | n/a |
GFS:P06860 | MAS-related GPR, member X1; Protien | Protien | n/a |