Symbol: Name: ID: |
KCNIP2 Kv channel interacting protein 2 GFS:4729 |
Gene name: | KCNIP2 |
Chromosome: | 10 |
Previous Symbols: | |
Previous Names: | Kv channel-interacting protein 2 |
Aliases: | KCHIP2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2135916 | Rat Genome Database ID: | RGD:70887 |
HGNC ID: | HGNC:15522 | RefSeq IDs: | NM_014591 |
Entrez Gene ID: | 30819 | Ensembl Gene ID: | ENSG00000120049 |
VEGA IDs: | OTTHUMG00000018937 | UniProt ID: | Q9NS61 |
UCSC ID: | uc001kuc.2 | OMIM ID: | 604661 |
Pubmed: | PMID10676964 | ||
CCDS IDs: | CCDSCCDS7521.1 CCDS CCDS7522.1 CCDS CCDS7523.1 CCDS CCDS7524.1 CCDS CCDS7525.1 CCDS CCDS7526.1 CCDS CCDS41562.1 |
Kv channel-interacting protein 2 also known as KChIP2 is a protein that in humans is encoded by the KCNIP2 gene.
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene. [provided by RefSeq, Jul 2008].
Function: Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Probably modulates channels density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND2/Kv4.2 and KCND3/Kv4.3 currents. Involved in KCND2 and KCND3 trafficking to the cell surface (By similarity).
Products for KCNIP2 gene
Catalog | Product Name | Application | Company |
GFS:E04729 | Kv channel interacting protein 2; ELISA kit | ELISA | n/a |
GFS:A04729 | Kv channel interacting protein 2; Anti | ANTIBODIES | n/a |
GFS:P04729 | Kv channel interacting protein 2; Protien | Protien | n/a |