Symbol: Name: ID: |
KCNIP1 Kv channel interacting protein 1 GFS:4728 |
Gene name: | KCNIP1 |
Chromosome: | 5q35 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KCHIP1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1917607 | Rat Genome Database ID: | RGD:70886 |
HGNC ID: | HGNC:15521 | RefSeq IDs: | NM_001034837 |
Entrez Gene ID: | 30820 | Ensembl Gene ID: | ENSG00000182132 |
VEGA IDs: | OTTHUMG00000130442 | UniProt ID: | Q9NZI2 |
UCSC ID: | uc003map.2 | OMIM ID: | 604660 |
Pubmed: | PMID10676964 | ||
CCDS IDs: | CCDSCCDS34285.1 CCDS CCDS34286.1 CCDS CCDS4374.1 |
Kv channel-interacting protein 1 also known as KChIP1 is a protein that in humans is encoded by the KCNIP1 gene.
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Alternative splicing results in multiple transcript variant encoding different isoforms. [provided by RefSeq, Jul 2008].
Function: Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Probably modulates channels density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND1/Kv4.1 and KCND2/Kv4.2 currents. Seems to be involved in KCND2 trafficking to the cell surface.
Products for KCNIP1 gene
Catalog | Product Name | Application | Company |
GFS:E04728 | Kv channel interacting protein 1; ELISA kit | ELISA | n/a |
GFS:A04728 | Kv channel interacting protein 1; Anti | ANTIBODIES | n/a |
GFS:P04728 | Kv channel interacting protein 1; Protien | Protien | n/a |