Symbol: Name: ID: |
EP400 E1A binding protein p400 GFS:1768 |
Gene name: | EP400 |
Chromosome: | 12q24.33 |
Previous Symbols: | TNRC12 |
Previous Names: | trinucleotide repeat containing 12 |
Aliases: | CAGH32, KIAA1498, P400, KIAA1818, DKFZP434I225 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1276124 | Rat Genome Database ID: | RGD:1304733 |
HGNC ID: | HGNC:11958 | RefSeq IDs: | NM_015409 |
Entrez Gene ID: | 57634 | Ensembl Gene ID: | ENSG00000183495 |
VEGA IDs: | UniProt ID: | Q96L91 | |
UCSC ID: | uc001ujl.2 | OMIM ID: | 606265 |
Pubmed: | PMID9225980 PMID 11509179 | ||
CCDS IDs: | CCDSCCDS31929.1 |
E1A-binding protein p400 is a protein that in humans is encoded by the EP400 gene.
Function: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. May regulate ZNF42 transcription activity.
Products for EP400 gene
Catalog | Product Name | Application | Company |
GFS:E01768 | E1A binding protein p400; ELISA kit | ELISA | n/a |
GFS:A01768 | E1A binding protein p400; Anti | ANTIBODIES | n/a |
GFS:P01768 | E1A binding protein p400; Protien | Protien | n/a |