Symbol: Name: ID: |
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 GFS:3752 |
Gene name: | DHX36 |
Chromosome: | 3p13-q23 |
Previous Symbols: | DDX36 |
Previous Names: | DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 36 |
Aliases: | MLEL1, KIAA1488 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1919412 | Rat Genome Database ID: | RGD:1308767 |
HGNC ID: | HGNC:14410 | RefSeq IDs: | NM_001114397 |
Entrez Gene ID: | 170506 | Ensembl Gene ID: | ENSG00000174953 |
VEGA IDs: | OTTHUMG00000159109 | UniProt ID: | Q9H2U1 |
UCSC ID: | uc003ezy.3 | OMIM ID: | 612767 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS3171.1 |
Probable ATP-dependent RNA helicase DHX36 also known as DEAH box protein 36 (DHX36) or MLE-like protein 1 (MLEL1) or G4 resolvase (G4R1) or RNA helicase associated with AU-rich elements (RHAU) is an enzyme that in humans is encoded by the DHX36 gene.
This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3'-UTR AU-rich elements (ARE-mRNA). The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
Function: Plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis.
Products for DHX36 gene
Catalog | Product Name | Application | Company |
GFS:E03752 | DEAH (Asp-Glu-Ala-His) box polypeptide 36; ELISA kit | ELISA | n/a |
GFS:A03752 | DEAH (Asp-Glu-Ala-His) box polypeptide 36; Anti | ANTIBODIES | n/a |
GFS:P03752 | DEAH (Asp-Glu-Ala-His) box polypeptide 36; Protien | Protien | n/a |