Symbol: Name: ID: |
DBF4 DBF4 homolog (S. cerevisiae) GFS:6443 |
Gene name: | DBF4 |
Chromosome: | 7q21.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | ASK, DBF4A, chif, ZDBF1 |
Name Aliases: | activator of S phase kinase, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1351328 | Rat Genome Database ID: | RGD:1305854 |
HGNC ID: | HGNC:17364 | RefSeq IDs: | NM_006716 |
Entrez Gene ID: | 10926 | Ensembl Gene ID: | ENSG00000006634 |
VEGA IDs: | OTTHUMG00000131034 | UniProt ID: | Q9UBU7 |
UCSC ID: | uc003ujf.1 | OMIM ID: | 604281 |
Pubmed: | PMID10373557 PMID 10517317 | ||
CCDS IDs: | CCDSCCDS5611.1 |
Protein DBF4 homolog A is a protein that in humans is encoded by the DBF4 gene.
Function: Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.
Products for DBF4 gene
Catalog | Product Name | Application | Company |
GFS:E06443 | DBF4 homolog (S. cerevisiae); ELISA kit | ELISA | n/a |
GFS:A06443 | DBF4 homolog (S. cerevisiae); Anti | ANTIBODIES | n/a |
GFS:P06443 | DBF4 homolog (S. cerevisiae); Protien | Protien | n/a |