Symbol: Name: ID: |
CADPS2 Ca++-dependent secretion activator 2 GFS:5148 |
Gene name: | CADPS2 |
Chromosome: | 7q31.32 |
Previous Symbols: | |
Previous Names: | Ca++-dependent activator protein for secretion 2 |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2443963 | Rat Genome Database ID: | RGD:1559440 |
HGNC ID: | HGNC:16018 | RefSeq IDs: | NM_001009571 |
Entrez Gene ID: | 93664 | Ensembl Gene ID: | ENSG00000081803 |
VEGA IDs: | OTTHUMG00000157093 | UniProt ID: | Q86UW7 |
UCSC ID: | uc010lkq.2 | OMIM ID: | 609978 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS47691.1 |
Calcium-dependent secretion activator 2 is a protein that in humans is encoded by the CADPS2 gene.
This gene encodes a member of the calcium-dependent activator of secretion (CAPS) protein family, which are calcium binding proteins that regulate the exocytosis of synaptic and dense-core vesicles in neurons and neuroendocrine cells. Mutations in this gene may contribute to autism susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2009].
Function: Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles (By similarity).
Products for CADPS2 gene
Catalog | Product Name | Application | Company |
GFS:E05148 | Ca++-dependent secretion activator 2; ELISA kit | ELISA | n/a |
GFS:A05148 | Ca++-dependent secretion activator 2; Anti | ANTIBODIES | n/a |
GFS:P05148 | Ca++-dependent secretion activator 2; Protien | Protien | n/a |