Symbol: Name: ID: |
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 GFS:6907 |
Gene name: | CDS2 |
Chromosome: | 20p13 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1332236 | Rat Genome Database ID: | RGD:621186 |
HGNC ID: | HGNC:1801 | RefSeq IDs: | NM_003818 |
Entrez Gene ID: | 8760 | Ensembl Gene ID: | ENSG00000101290 |
VEGA IDs: | OTTHUMG00000031801 | UniProt ID: | O95674 |
UCSC ID: | uc002wls.2 | OMIM ID: | 603549 |
Pubmed: | PMID9806839 PMID 9889000 | ||
CCDS IDs: | CCDSCCDS13088.1 |
Phosphatidate cytidylyltransferase 2 is an enzyme that in humans is encoded by the CDS2 gene.
Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13. [provided by RefSeq, Jul 2008]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
Function: Provides CDP-diacylglycerol an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.
Products for CDS2 gene
Catalog | Product Name | Application | Company |
GFS:E06907 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2; ELISA kit | ELISA | n/a |
GFS:A06907 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2; Anti | ANTIBODIES | n/a |
GFS:P06907 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2; Protien | Protien | n/a |