Symbol: Name: ID: |
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 GFS:6896 |
Gene name: | CDS1 |
Chromosome: | 4q21 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1921846 | Rat Genome Database ID: | RGD:621185 |
HGNC ID: | HGNC:1800 | RefSeq IDs: | NM_001263 |
Entrez Gene ID: | 1040 | Ensembl Gene ID: | ENSG00000163624 |
VEGA IDs: | OTTHUMG00000130428 | UniProt ID: | Q92903 |
UCSC ID: | uc011ccv.1 | OMIM ID: | 603548 |
Pubmed: | PMID9806839 PMID 9115637 | ||
CCDS IDs: | CCDSCCDS3608.1 |
Phosphatidate cytidylyltransferase 1 is an enzyme that in humans is encoded by the CDS1 gene.
Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13. [provided by RefSeq, Jul 2008].
Function: Provides CDP-diacylglycerol an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin. Overexpression may amplify cellular signaling responses from cytokines. May also play an important role in the signal transduction mechanism of retina and neural cells.
Products for CDS1 gene
Catalog | Product Name | Application | Company |
GFS:E06896 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1; ELISA kit | ELISA | n/a |
GFS:A06896 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1; Anti | ANTIBODIES | n/a |
GFS:P06896 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1; Protien | Protien | n/a |