Symbol: Name: ID: |
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like GFS:762 |
Gene name: | BNIP3L |
Chromosome: | 8p21 |
Previous Symbols: | |
Previous Names: | BCL2/adenovirus E1B 19kD-interacting protein 3-like |
Aliases: | Nix, BNIP3a |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1332659 | Rat Genome Database ID: | |
HGNC ID: | HGNC:1085 | RefSeq IDs: | NM_004331 |
Entrez Gene ID: | 665 | Ensembl Gene ID: | ENSG00000104765 |
VEGA IDs: | OTTHUMG00000099433 | UniProt ID: | O60238 |
UCSC ID: | uc003xex.1 | OMIM ID: | 605368 |
Pubmed: | PMID9523198 PMID 9973195 | ||
CCDS IDs: | CCDSCCDS6050.1 |
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like is a protein that in humans is encoded by the BNIP3L gene. This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. This protein counteracts the apoptotic inducer BNIP3 and may play a role in tumor suppression. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. May function as a tumor suppressor.
Products for BNIP3L gene
Catalog | Product Name | Application | Company |
GFS:E00762 | BCL2/adenovirus E1B 19kDa interacting protein 3-like; ELISA kit | ELISA | n/a |
GFS:A00762 | BCL2/adenovirus E1B 19kDa interacting protein 3-like; Anti | ANTIBODIES | n/a |
GFS:P00762 | BCL2/adenovirus E1B 19kDa interacting protein 3-like; Protien | Protien | n/a |