Symbol: Name: ID: |
ZNF384 zinc finger protein 384 GFS:1766 |
Gene name: | ZNF384 |
Chromosome: | 12p12 |
Previous Symbols: | TNRC1 |
Previous Names: | trinucleotide repeat containing 1 |
Aliases: | CAGH1A, CIZ, NMP4, NP |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2443203 | Rat Genome Database ID: | RGD:708346 |
HGNC ID: | HGNC:11955 | RefSeq IDs: | NM_001039916 |
Entrez Gene ID: | 171017 | Ensembl Gene ID: | ENSG00000126746 |
VEGA IDs: | UniProt ID: | Q8TF68 | |
UCSC ID: | uc010sfh.1 | OMIM ID: | 609951 |
Pubmed: | PMID9225980 PMID 11149472 | ||
CCDS IDs: | CCDSCCDS8557.1 CCDS CCDS31732.1 CCDS CCDS41742.1 CCDS CCDS44817.1 |
Zinc finger protein 384 is a protein that in humans is encoded by the ZNF384 gene. This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq].
Transcription factor that binds the consensus DNA sequence [GC]AAAAA. Seems to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1 (By similarity).
Products for ZNF384 gene
Catalog | Product Name | Application | Company |
GFS:E01766 | zinc finger protein 384; ELISA kit | ELISA | n/a |
GFS:A01766 | zinc finger protein 384; Anti | ANTIBODIES | n/a |
GFS:P01766 | zinc finger protein 384; Protien | Protien | n/a |