Symbol: Name: ID: |
ZGPAT zinc finger, CCCH-type with G patch domain GFS:5079 |
Gene name: | ZGPAT |
Chromosome: | 20q13.3 |
Previous Symbols: | KIAA1847 |
Previous Names: | KIAA1847 |
Aliases: | dJ583P15.3, MGC44880, FLJ14972, ZC3HDC9, ZC3H9, GPATC6, GPATCH6, ZIP |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2449939 | Rat Genome Database ID: | RGD:1310801 |
HGNC ID: | HGNC:15948 | RefSeq IDs: | NM_001083113 |
Entrez Gene ID: | 84619 | Ensembl Gene ID: | ENSG00000197114 |
VEGA IDs: | OTTHUMG00000032998 | UniProt ID: | Q8N5A5 |
UCSC ID: | uc002ygk.2 | OMIM ID: | |
Pubmed: | PMID16952911 | ||
CCDS IDs: | CCDSCCDS13534.1 CCDS CCDS13535.1 |
Zinc finger CCCH-type with G patch domain-containing protein is a protein that in humans is encoded by the ZGPAT gene.
Function: Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis.
Products for ZGPAT gene
Catalog | Product Name | Application | Company |
GFS:E05079 | zinc finger, CCCH-type with G patch domain; ELISA kit | ELISA | n/a |
GFS:A05079 | zinc finger, CCCH-type with G patch domain; Anti | ANTIBODIES | n/a |
GFS:P05079 | zinc finger, CCCH-type with G patch domain; Protien | Protien | n/a |