Symbol: Name: ID: |
ZFAND5 zinc finger, AN1-type domain 5 GFS:2714 |
Gene name: | ZFAND5 |
Chromosome: | 9q13-q21 |
Previous Symbols: | ZNF216, ZA20D2 |
Previous Names: | zinc finger protein 216, "zinc finger, A20 domain containing 2" |
Aliases: | ZFAND5A |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1278334 | Rat Genome Database ID: | RGD:1310776 |
HGNC ID: | HGNC:13008 | RefSeq IDs: | NM_001102420 |
Entrez Gene ID: | 7763 | Ensembl Gene ID: | ENSG00000107372 |
VEGA IDs: | OTTHUMG00000020008 | UniProt ID: | O76080 |
UCSC ID: | uc004aiy.2 | OMIM ID: | 604761 |
Pubmed: | PMID9758550 | ||
CCDS IDs: | CCDSCCDS6642.1 |
Function: Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Could be involved in regulating NF-kappa-B activation and apoptosis. Is a potent inhibitory factor for osteoclast differentiation. Involved in protein degradation via the ubiquitin-proteasome system and plays a critical role in muscle atrophy. May act by anchoring ubiquitinylated proteins to the proteasome, playing a critical role in protein degradation.
Products for ZFAND5 gene
Catalog | Product Name | Application | Company |
GFS:E02714 | zinc finger, AN1-type domain 5; ELISA kit | ELISA | n/a |
GFS:A02714 | zinc finger, AN1-type domain 5; Anti | ANTIBODIES | n/a |
GFS:P02714 | zinc finger, AN1-type domain 5; Protien | Protien | n/a |