| Symbol: Name: ID: |
VEZT vezatin, adherens junctions transmembrane protein GFS:7128 |
| Gene name: | VEZT |
| Chromosome: | 12q22 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | DKFZP761C241 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:2143698 | Rat Genome Database ID: | RGD:1359117 |
| HGNC ID: | HGNC:18258 | RefSeq IDs: | NM_017599 |
| Entrez Gene ID: | 55591 | Ensembl Gene ID: | ENSG00000028203 |
| VEGA IDs: | UniProt ID: | Q9HBM0 | |
| UCSC ID: | uc001tdz.2 | OMIM ID: | |
| Pubmed: | PMID11080149 PMID 16199027 PMID 21156161 | ||
| CCDS IDs: | CCDSCCDS44954.1 | ||
Vezatin is a protein that in humans is encoded by the VEZT gene.
This gene encodes a transmembrane protein which has been localized to adherens junctions and shown to bind to myosin VIIA. Examination of expression of this gene in gastric cancer tissues have shown that expression is decreased which appears to be related to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific microRNA to a target sequence in the 3' UTR of the transcripts. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011].
Function: Plays a pivotal role in the establishment of adherens junctions and their maintenance in adult life. In case of Listeria infection, promotes bacterial internalization by participating to myosin VIIa recruitment to the entry site.
Products for VEZT gene
| Catalog | Product Name | Application | Company |
| GFS:E07128 | vezatin, adherens junctions transmembrane protein; ELISA kit | ELISA | n/a |
| GFS:A07128 | vezatin, adherens junctions transmembrane protein; Anti | ANTIBODIES | n/a |
| GFS:P07128 | vezatin, adherens junctions transmembrane protein; Protien | Protien | n/a |
