Symbol: Name: ID: |
VANGL2 vang-like 2 (van gogh, Drosophila) GFS:4717 |
Gene name: | VANGL2 |
Chromosome: | 1q22-q23 |
Previous Symbols: | |
Previous Names: | vang (van gogh, Drosophila)-like 2, vang, van gogh-like 2 (Drosophila) |
Aliases: | KIAA1215, LTAP, LPP1, STBM, STB1, STBM1, MGC119403, MGC119404 |
Name Aliases: | vang, van gogh-like 2, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2135272 | Rat Genome Database ID: | RGD:1309442 |
HGNC ID: | HGNC:15511 | RefSeq IDs: | NM_020335 |
Entrez Gene ID: | 57216 | Ensembl Gene ID: | ENSG00000162738 |
VEGA IDs: | OTTHUMG00000033122 | UniProt ID: | Q9ULK5 |
UCSC ID: | uc001fwc.1 | OMIM ID: | 600533 |
Pubmed: | PMID11431695 | ||
CCDS IDs: | CCDSCCDS30915.1 |
The protein encoded by this gene is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea. The encoded protein transmits directional signals to individual cells or groups of cells in epithelial sheets. This protein is also involved in the development of the neural plate. [provided by RefSeq, Sep 2011]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
Function: Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process (By similarity).
Products for VANGL2 gene
Catalog | Product Name | Application | Company |
GFS:E04717 | vang-like 2 (van gogh, Drosophila); ELISA kit | ELISA | n/a |
GFS:A04717 | vang-like 2 (van gogh, Drosophila); Anti | ANTIBODIES | n/a |
GFS:P04717 | vang-like 2 (van gogh, Drosophila); Protien | Protien | n/a |