Symbol: Name: ID: |
SKI v-ski sarcoma viral oncogene homolog (avian) GFS:803 |
Gene name: | SKI |
Chromosome: | 1q22-q24 |
Previous Symbols: | |
Previous Names: | v-ski avian sarcoma viral oncogene homolog |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98310 | Rat Genome Database ID: | |
HGNC ID: | HGNC:10896 | RefSeq IDs: | NM_003036 |
Entrez Gene ID: | 6497 | Ensembl Gene ID: | ENSG00000157933 |
VEGA IDs: | OTTHUMG00000001407 | UniProt ID: | P12755 |
UCSC ID: | uc001aja.3 | OMIM ID: | 164780 |
Pubmed: | PMID2762147 | ||
CCDS IDs: | CCDSCCDS39.1 |
The Ski protein is a nuclear protooncoprotein that is associated with tumors at high cellular concentrations. Ski has been shown to interfere with normal cellular functioning by both directly impeding expression of certain genes inside the nucleus of the cell as well as disrupting signaling proteins that activate genes. This gene encodes the nuclear protooncogene protein homolog of avian sarcoma viral (v-ski) oncogene. It functions as a repressor of TGF-beta signaling, and may play a role in neural tube development and muscle differentiation. [provided by RefSeq]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Functions as a repressor of TGF-beta signaling.
Products for SKI gene
Catalog | Product Name | Application | Company |
GFS:E00803 | v-ski sarcoma viral oncogene homolog (avian); ELISA kit | ELISA | n/a |
GFS:A00803 | v-ski sarcoma viral oncogene homolog (avian); Anti | ANTIBODIES | n/a |
GFS:P00803 | v-ski sarcoma viral oncogene homolog (avian); Protien | Protien | n/a |