Symbol: Name: ID: |
UROD uroporphyrinogen decarboxylase GFS:2374 |
Gene name: | UROD |
Chromosome: | 1p34 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98916 | Rat Genome Database ID: | RGD:3946 |
HGNC ID: | HGNC:12591 | RefSeq IDs: | NM_000374 |
Entrez Gene ID: | 7389 | Ensembl Gene ID: | ENSG00000126088 |
VEGA IDs: | OTTHUMG00000008949 | UniProt ID: | P06132 |
UCSC ID: | uc001cna.1 | OMIM ID: | 613521 |
Pubmed: | PMID3015909 PMID 3460962 | ||
CCDS IDs: | CCDSCCDS518.1 |
Uroporphyrinogen decarboxylase, also known as UROD, is an enzyme which in humans is encoded by the UROD gene.
This gene encodes an enzyme in the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.
Function: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
Products for UROD gene
Catalog | Product Name | Application | Company |
GFS:E02374 | uroporphyrinogen decarboxylase; ELISA kit | ELISA | n/a |
GFS:A02374 | uroporphyrinogen decarboxylase; Anti | ANTIBODIES | n/a |
GFS:P02374 | uroporphyrinogen decarboxylase; Protien | Protien | n/a |