Symbol: Name: ID: |
UCN urocortin GFS:2307 |
Gene name: | UCN |
Chromosome: | 2p23-p21 |
Previous Symbols: | |
Previous Names: | |
Aliases: | UROC, UI |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1276123 | Rat Genome Database ID: | RGD:3929 |
HGNC ID: | HGNC:12516 | RefSeq IDs: | NM_003353 |
Entrez Gene ID: | 7349 | Ensembl Gene ID: | ENSG00000163794 |
VEGA IDs: | OTTHUMG00000097068 | UniProt ID: | P55089 |
UCSC ID: | uc002rjp.1 | OMIM ID: | 600945 |
Pubmed: | PMID9628819 PMID 861256 | ||
CCDS IDs: | CCDSCCDS1747.1 |
Urocortin is a protein that in humans is encoded by the UCN gene.
This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH). Binds with high affinity to CRF Receptor types 1, 2-alpha, and 2-beta.
Products for UCN gene
Catalog | Product Name | Application | Company |
GFS:E02307 | urocortin; ELISA kit | ELISA | n/a |
GFS:A02307 | urocortin; Anti | ANTIBODIES | n/a |
GFS:P02307 | urocortin; Protien | Protien | n/a |