| Symbol: Name: ID: |
UPP1 uridine phosphorylase 1 GFS:2360 |
| Gene name: | UPP1 |
| Chromosome: | 7p12.3 |
| Previous Symbols: | UP |
| Previous Names: | uridine phosphorylase |
| Aliases: | UPASE, UPP, UDRPASE |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1097668 | Rat Genome Database ID: | RGD:1305566 |
| HGNC ID: | HGNC:12576 | RefSeq IDs: | NM_003364 |
| Entrez Gene ID: | 7378 | Ensembl Gene ID: | ENSG00000183696 |
| VEGA IDs: | OTTHUMG00000129253 | UniProt ID: | Q16831 |
| UCSC ID: | uc003toj.2 | OMIM ID: | 191730 |
| Pubmed: | PMID752472 PMID 11807789 | ||
| CCDS IDs: | CCDSCCDS5507.1 | ||
Uridine phosphorylase 1 is an enzyme that in humans is encoded by the UPP1 gene.
The 2 known types of pyrimidine nucleoside phosphorylases, uridine phosphorylase (UP; EC 2.4.2.3) and thymidine phosphorylase (TP; EC 2.4.2.4), in the presence of orthophosphate, catalyze the reversible phosphorolysis of uridine and thymidine or deoxyuridine, respectively, to free bases and ribose-1-phosphate or deoxyribose-1-phosphate. Pyrimidine nucleoside phosphorylases can add ribose or deoxyribose to pyrimidine bases to form nucleosides that can be incorporated into RNA or DNA (Watanabe and Uchida, 1995 [PubMed 7488099]).[supplied by OMIM].
Function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
Products for UPP1 gene
| Catalog | Product Name | Application | Company |
| GFS:E02360 | uridine phosphorylase 1; ELISA kit | ELISA | n/a |
| GFS:A02360 | uridine phosphorylase 1; Anti | ANTIBODIES | n/a |
| GFS:P02360 | uridine phosphorylase 1; Protien | Protien | n/a |
