Symbol: Name: ID: |
UBASH3A ubiquitin associated and SH3 domain containing A GFS:2254 |
Gene name: | UBASH3A |
Chromosome: | 21q22.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | STS-2, TULA, CLIP4 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1926074 | Rat Genome Database ID: | RGD:1310305 |
HGNC ID: | HGNC:12462 | RefSeq IDs: | NM_001001895 |
Entrez Gene ID: | 53347 | Ensembl Gene ID: | ENSG00000160185 |
VEGA IDs: | OTTHUMG00000086805 | UniProt ID: | P57075 |
UCSC ID: | uc002zbf.2 | OMIM ID: | 605736 |
Pubmed: | PMID11281453 | ||
CCDS IDs: | CCDSCCDS13687.1 CCDS CCDS33566.1 |
Ubiquitin-associated and SH3 domain-containing protein A is a protein that in humans is encoded by the UBASH3A gene.
Function: Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle phosphatase activity. May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain.
Products for UBASH3A gene
Catalog | Product Name | Application | Company |
GFS:E02254 | ubiquitin associated and SH3 domain containing A; ELISA kit | ELISA | n/a |
GFS:A02254 | ubiquitin associated and SH3 domain containing A; Anti | ANTIBODIES | n/a |
GFS:P02254 | ubiquitin associated and SH3 domain containing A; Protien | Protien | n/a |