Symbol: Name: ID: |
YARS tyrosyl-tRNA synthetase GFS:2590 |
Gene name: | YARS |
Chromosome: | 1p35.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | YTS, YRS, tyrRS |
Name Aliases: | tyrosine tRNA ligase 1, cytoplasmic |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2147627 | Rat Genome Database ID: | RGD:1307616 |
HGNC ID: | HGNC:12840 | RefSeq IDs: | NM_003680 |
Entrez Gene ID: | 8565 | Ensembl Gene ID: | ENSG00000134684 |
VEGA IDs: | OTTHUMG00000003933 | UniProt ID: | P54577 |
UCSC ID: | uc001bvy.1 | OMIM ID: | 603623 |
Pubmed: | PMID8552597 PMID 9162081 | ||
CCDS IDs: | CCDSCCDS368.1 |
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. [provided by RefSeq]. Sequence Note: The RefSeq transhttp://www.ncbi.nlm.nih.gov/projects/locusXref/oho.cgi?server= REFTRACK&frm=0x66adf650&appid=0&evId=1&evIntpar=8565&evStrpar=&frmA n=EditApp LocusXref: edit YARS(8565)cript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for YARS gene
Catalog | Product Name | Application | Company |
GFS:E02590 | tyrosyl-tRNA synthetase; ELISA kit | ELISA | n/a |
GFS:A02590 | tyrosyl-tRNA synthetase; Anti | ANTIBODIES | n/a |
GFS:P02590 | tyrosyl-tRNA synthetase; Protien | Protien | n/a |