Symbol: Name: ID: |
TNK1 tyrosine kinase, non-receptor, 1 GFS:1752 |
Gene name: | TNK1 |
Chromosome: | 17p13.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1930958 | Rat Genome Database ID: | RGD:1310113 |
HGNC ID: | HGNC:11940 | RefSeq IDs: | NM_003985 |
Entrez Gene ID: | 8711 | Ensembl Gene ID: | ENSG00000174292 |
VEGA IDs: | UniProt ID: | Q13470 | |
UCSC ID: | uc002ggj.3 | OMIM ID: | 608076 |
Pubmed: | PMID8632913 | ||
CCDS IDs: | CCDSCCDS45602.1 |
TNK1 is a nonreceptor tyrosine kinase. These kinases, like members of the SRC (MIM 190090) and JAK (see MIM 147795) families, mediate intracellular signaling downstream of receptor activation.[supplied by OMIM]. Sequence Note: removed 1 base from the 5' end that did not align to the reference genome assembly.
Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction.
Products for TNK1 gene
Catalog | Product Name | Application | Company |
GFS:E01752 | tyrosine kinase, non-receptor, 1; ELISA kit | ELISA | n/a |
GFS:A01752 | tyrosine kinase, non-receptor, 1; Anti | ANTIBODIES | n/a |
GFS:P01752 | tyrosine kinase, non-receptor, 1; Protien | Protien | n/a |