Symbol: Name: ID: |
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide GFS:2602 |
Gene name: | YWHAZ |
Chromosome: | 8q22.3 |
Previous Symbols: | YWHAD |
Previous Names: | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, delta polypeptide |
Aliases: | KCIP-1, 14-3-3-zeta |
Name Aliases: | 14-3-3 zeta, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:109484 | Rat Genome Database ID: | RGD:3980 |
HGNC ID: | HGNC:12855 | RefSeq IDs: | NM_001135699 |
Entrez Gene ID: | 7534 | Ensembl Gene ID: | ENSG00000164924 |
VEGA IDs: | OTTHUMG00000134291 | UniProt ID: | P63104 |
UCSC ID: | uc010mbr.2 | OMIM ID: | 601288 |
Pubmed: | PMID8617504 PMID 7890696 | ||
CCDS IDs: | CCDSCCDS6290.1 |
14-3-3 protein zeta/delta is a protein that in humans is encoded by the YWHAZ gene.
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq].
Function: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
Products for YWHAZ gene
Catalog | Product Name | Application | Company |
GFS:E02602 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; ELISA kit | ELISA | n/a |
GFS:A02602 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; Anti | ANTIBODIES | n/a |
GFS:P02602 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; Protien | Protien | n/a |