Symbol: Name: ID: |
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide GFS:2601 |
Gene name: | YWHAQ |
Chromosome: | 2p25.2-p25.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | HS1, 14-3-3 |
Name Aliases: | protein tau |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:891963 | Rat Genome Database ID: | RGD:3979 |
HGNC ID: | HGNC:12854 | RefSeq IDs: | NM_006826 |
Entrez Gene ID: | 10971 | Ensembl Gene ID: | ENSG00000134308 |
VEGA IDs: | OTTHUMG00000013848 | UniProt ID: | P27348 |
UCSC ID: | uc002qzx.2 | OMIM ID: | 609009 |
Pubmed: | PMID11080204 | ||
CCDS IDs: | CCDSCCDS1666.1 |
14-3-3 protein theta is a protein that in humans is encoded by the YWHAQ gene.
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
Products for YWHAQ gene
Catalog | Product Name | Application | Company |
GFS:E02601 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide; ELISA kit | ELISA | n/a |
GFS:A02601 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide; Anti | ANTIBODIES | n/a |
GFS:P02601 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide; Protien | Protien | n/a |