Symbol: Name: ID: |
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide GFS:2596 |
Gene name: | YWHAB |
Chromosome: | 20q13.1 |
Previous Symbols: | YWHAA |
Previous Names: | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide |
Aliases: | |
Name Aliases: | 14-3-3 beta, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1891917 | Rat Genome Database ID: | RGD:61998 |
HGNC ID: | HGNC:12849 | RefSeq IDs: | NM_003404 |
Entrez Gene ID: | 7529 | Ensembl Gene ID: | ENSG00000166913 |
VEGA IDs: | OTTHUMG00000032549 | UniProt ID: | P31946 |
UCSC ID: | uc002xmt.2 | OMIM ID: | 601289 |
Pubmed: | PMID8617504 PMID 7890696 | ||
CCDS IDs: | CCDSCCDS13339.1 |
14-3-3 protein beta/alpha is a protein that in humans is encoded by the YWHAB gene.
This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq].
Function: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis.
Products for YWHAB gene
Catalog | Product Name | Application | Company |
GFS:E02596 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide; ELISA kit | ELISA | n/a |
GFS:A02596 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide; Anti | ANTIBODIES | n/a |
GFS:P02596 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide; Protien | Protien | n/a |