| Symbol: Name: ID: |
TWSG1 twisted gastrulation homolog 1 (Drosophila) GFS:2229 |
| Gene name: | TWSG1 |
| Chromosome: | 18p11.3 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | TSG |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:2137520 | Rat Genome Database ID: | RGD:1311215 |
| HGNC ID: | HGNC:12429 | RefSeq IDs: | NM_020648 |
| Entrez Gene ID: | 57045 | Ensembl Gene ID: | ENSG00000128791 |
| VEGA IDs: | OTTHUMG00000131597 | UniProt ID: | Q9GZX9 |
| UCSC ID: | uc002knz.2 | OMIM ID: | 605049 |
| Pubmed: | PMID11260715 | ||
| CCDS IDs: | CCDSCCDS11844.1 | ||
Twisted gastrulation protein homolog 1 is a protein that in humans is encoded by the TWSG1 gene.
May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity).
Products for TWSG1 gene
| Catalog | Product Name | Application | Company |
| GFS:E02229 | twisted gastrulation homolog 1 (Drosophila); ELISA kit | ELISA | n/a |
| GFS:A02229 | twisted gastrulation homolog 1 (Drosophila); Anti | ANTIBODIES | n/a |
| GFS:P02229 | twisted gastrulation homolog 1 (Drosophila); Protien | Protien | n/a |
