Symbol: Name: ID: |
TDRD1 tudor domain containing 1 GFS:1530 |
Gene name: | TDRD1 |
Chromosome: | 10q26.11 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CT41.1 |
Name Aliases: | cancer/testis antigen 41.1 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1933218 | Rat Genome Database ID: | RGD:1306140 |
HGNC ID: | HGNC:11712 | RefSeq IDs: | NM_198795 |
Entrez Gene ID: | 56165 | Ensembl Gene ID: | ENSG00000095627 |
VEGA IDs: | OTTHUMG00000019083 | UniProt ID: | Q9BXT4 |
UCSC ID: | uc001lbg.1 | OMIM ID: | 605796 |
Pubmed: | PMID11279525 | ||
CCDS IDs: | CCDSCCDS7588.1 |
The TDRD1 gene is similar to a mouse gene that encodes a tudor domain protein. Alternatively spliced transcript variants have been described but their full length sequences have not been determined. [provided by RefSeq].
Plays a central role during spermatogenesis by participating to the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of correct transcripts into the normal piRNA pool and limiting the entry of cellular transcripts into the piRNA pathway. May act by allowing the recruitment of piRNA biogenesis or loading factors that ensure the correct entry of transcripts and piRNAs into Piwi proteins (By similarity).
Products for TDRD1 gene
Catalog | Product Name | Application | Company |
GFS:E01530 | tudor domain containing 1; ELISA kit | ELISA | n/a |
GFS:A01530 | tudor domain containing 1; Anti | ANTIBODIES | n/a |
GFS:P01530 | tudor domain containing 1; Protien | Protien | n/a |