Symbol: Name: ID: |
TBCE tubulin folding cofactor E GFS:1433 |
Gene name: | TBCE |
Chromosome: | 1q42.3 |
Previous Symbols: | KCS |
Previous Names: | tubulin-specific chaperone e, "Kenny-Caffey syndrome" |
Aliases: | HRD, KCS1, pac2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1917680 | Rat Genome Database ID: | RGD:1305533 |
HGNC ID: | HGNC:11582 | RefSeq IDs: | NM_001079515 |
Entrez Gene ID: | 6905 | Ensembl Gene ID: | ENSG00000116957 |
VEGA IDs: | OTTHUMG00000039987 | UniProt ID: | Q15813 |
UCSC ID: | uc001hxa.1 | OMIM ID: | 604934 |
Pubmed: | PMID8706133 PMID 9806825 PMID 12389028 | ||
CCDS IDs: | CCDSCCDS1605.1 |
Tubulin-specific chaperone E is a protein that in humans is encoded by the TBCE gene. Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
Tubulin-folding protein; involved in the second step of the tubulin folding pathway. Seems to be implicated in the maintenance of the neuronal microtubule network. Involved in regulation of tubulin heterodimer dissociation.
Products for TBCE gene
Catalog | Product Name | Application | Company |
GFS:E01433 | tubulin folding cofactor E; ELISA kit | ELISA | n/a |
GFS:A01433 | tubulin folding cofactor E; Anti | ANTIBODIES | n/a |
GFS:P01433 | tubulin folding cofactor E; Protien | Protien | n/a |