Symbol: Name: ID: |
TUBG2 tubulin, gamma 2 GFS:2220 |
Gene name: | TUBG2 |
Chromosome: | 17q21.31 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2144208 | Rat Genome Database ID: | RGD:1585798 |
HGNC ID: | HGNC:12419 | RefSeq IDs: | NM_016437 |
Entrez Gene ID: | 27175 | Ensembl Gene ID: | ENSG00000037042 |
VEGA IDs: | UniProt ID: | Q9NRH3 | |
UCSC ID: | uc010wgr.1 | OMIM ID: | 605785 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS32658.1 |
Tubulin gamma-2 chain is a protein that in humans is encoded by the TUBG2 gene. Tubulin is the major constituent of microtubules. Gamma tubulin is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.
Microtubules are cylindrical tubes of 20-25 nm in diameter. They are composed of protofilaments which are in turn composed of alpha- and beta-tubulin polymers. Each microtubule is polarized, at one end alpha-subunits are exposed (-) and at the other beta-subunits are exposed (+). Microtubules act as a scaffold to determine cell shape, and provide a backbone for cell organelles and vesicles to move on, a process that requires motor proteins. The major microtubule motor proteins are kinesin, which generally moves towards the (+) end of the microtubule, and dynein, which generally moves towards the (-) end. Microtubules also form the spindle fibers for separating chromosomes during mitosis.
Products for TUBG2 gene
Catalog | Product Name | Application | Company |
GFS:E02220 | tubulin, gamma 2; ELISA kit | ELISA | n/a |
GFS:A02220 | tubulin, gamma 2; Anti | ANTIBODIES | n/a |
GFS:P02220 | tubulin, gamma 2; Protien | Protien | n/a |