Symbol: Name: ID: |
TNRC6A trinucleotide repeat containing 6A GFS:1775 |
Gene name: | TNRC6A |
Chromosome: | 16p11.2 |
Previous Symbols: | TNRC6 |
Previous Names: | trinucleotide repeat containing 6 |
Aliases: | CAGH26, KIAA1460, GW182 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2385292 | Rat Genome Database ID: | RGD:1307268 |
HGNC ID: | HGNC:11969 | RefSeq IDs: | NM_014494 |
Entrez Gene ID: | 27327 | Ensembl Gene ID: | ENSG00000090905 |
VEGA IDs: | OTTHUMG00000096999 | UniProt ID: | Q8NDV7 |
UCSC ID: | uc002dmm.2 | OMIM ID: | 610739 |
Pubmed: | PMID9225980 | ||
CCDS IDs: | CCDSCCDS10624.2 |
Trinucleotide repeat-containing gene 6A protein is a protein that in humans is encoded by the TNRC6A gene. This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent repression of translation and for siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins.
Products for TNRC6A gene
Catalog | Product Name | Application | Company |
GFS:E01775 | trinucleotide repeat containing 6A; ELISA kit | ELISA | n/a |
GFS:A01775 | trinucleotide repeat containing 6A; Anti | ANTIBODIES | n/a |
GFS:P01775 | trinucleotide repeat containing 6A; Protien | Protien | n/a |