Symbol: Name: ID: |
TREM1 triggering receptor expressed on myeloid cells 1 GFS:6675 |
Gene name: | TREM1 |
Chromosome: | 6p21.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | TREM-1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1930005 | Rat Genome Database ID: | RGD:1309467 |
HGNC ID: | HGNC:17760 | RefSeq IDs: | NM_018643 |
Entrez Gene ID: | 54210 | Ensembl Gene ID: | ENSG00000124731 |
VEGA IDs: | OTTHUMG00000014674 | UniProt ID: | Q9NP99 |
UCSC ID: | uc003oqf.1 | OMIM ID: | 605085 |
Pubmed: | PMID11922939 PMID 10799849 | ||
CCDS IDs: | CCDSCCDS4854.1 |
Triggering receptor expressed on myeloid cells 1 is a protein that in humans is encoded by the TREM1 gene.
This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011].
Function: Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock.
Products for TREM1 gene
Catalog | Product Name | Application | Company |
GFS:E06675 | triggering receptor expressed on myeloid cells 1; ELISA kit | ELISA | n/a |
GFS:A06675 | triggering receptor expressed on myeloid cells 1; Anti | ANTIBODIES | n/a |
GFS:P06675 | triggering receptor expressed on myeloid cells 1; Protien | Protien | n/a |